(1) MEDICAL CYBERNETIC ELEMENTS IN COMPUTERIZED ASSISTED INTENSIVE THERAPY IN DOGS
(2) VISUAL PARADIGM OVER LOGICAL CIRCUITS IN VETERINARY MEDICINE
(3) OBSERVATIONS FOR OBTEINING THE ULTRAFINS SECTIONS ON THE LKB ULTROTOME
IN COMPUTERIZED ASSISTED INTENSIVE THERAPY IN DOGS
Authors: Cumpănaşu Florin, Surdu Cristina, Marcoci Mihaela Steliana, Preoteasa Luciana
Scientific coordinators:
Lecturer,
SUMMARY
The performances of a computerized assisted intensive therapy relay on the logical consistency of the cybernetics circuit used by the involved artificial intelligence agent involved.
To explore the possibility to transpose the real homeostatic cybernetics into an informational environment, we developed a medical Integrated Development Environment (IDE) composed of a relational database and the needed tools used for virtualization, testing and simulation.
Our IDE is based on the uses of an intermediate language between the natural language and the numerical internal representation of the artificial intelligence agent. From the point of view of a human agent, the direct usage of the IDE is limited by the intermediate language grammatical requirements. From the point of view of a developer, the intermediate restricted language is useful for 1) message forwarding; 2) decision priority transfer as control-flow; 3) threading complex tasks; 4) manipulating artificial effectors; 5) system integration with tried party application; 6) test and log events;
The capability of the computerized agent to virtualizes and handle relations between fundamental physiological processes is exemplified in the case of query derived usage of the IDE. We considered essential for the dog intensive therapy, some logical circuits of medical cybernetics related to the post-aggressive systemic reaction. In respect with this assumption we structured the informational-decisional system that explores cybernetic relations related to hypoxia, metabolic acidosis, tachycardia, arterial hypotension, adrenaline, glycemia and calcemia.
Further development guidelines for this theme involve the basic arithmetic computation compatibility, basic logical operations compatibility and the development of a programming language for medical use that can be used based on medical knowledge.
References:
1. James K.; James S. (1998). Mathematical Physilogy. Springer-Verlag, New-York.
2. Teodorescu E. (1968). Agresologie Chirurgicală. Editura Medicală, Bucureşti.
3.
(1) MEDICAL CYBERNETIC ELEMENTS IN COMPUTERIZED ASSISTED INTENSIVE THERAPY IN DOGS
(2) VISUAL PARADIGM OVER LOGICAL CIRCUITS IN VETERINARY MEDICINE
(3) OBSERVATIONS FOR OBTEINING THE ULTRAFINS SECTIONS ON THE LKB ULTROTOME
VISUAL PARADIGM OVER LOGICAL
CIRCUITS
IN VETERINARY MEDICINE
Authors:
Drăgan Gabriela, Aoanei
Monica Adriana, Cumpănaşu Florin
Scientific
coordinators: Lecturer, Giurgiu Gavril
University of Agricultural Sciences and
Veterinary Medicine, Cluj-Napoca, Faculty of Veterinary Medicine, 3-5 Manastur Street, 400372, Cluj-Napoca, Romania, email: gabi_18d@yahoo.com
SUMMARY
Decisions in veterinary practice are based on a good manage of logical circuits. Short time of reaction can be obtained if the overall image that encloses the physiology, physiopathology and metabolism can be recalled. The subject of this work is to explore the basic logical circuits of animal homeostasis trough a visual paradigm over the logical circuits involved.
To represent dynamic processes in a static context, unified modeling language UML is used from inside Visual Paradigm trail. Use case diagrams, class diagrams, object diagrams and state machine diagrams are generated. To represent dynamic processes in a dynamic content Wolfram Mathematica trail and 3DS max Studio from Autodesk trail are used.
Our main concern is directed toward the representation of hypoxia, metabolic acidosis, tachycardia, arterial hypotension, adrenaline, glycemia and calcemia and their interdependences. A simple case is that of the enclosed circle created by collagen hydratation acidic environment, increased edema, decreased tissue perfusion, increased hypoxia, increased metabolic acidity.
Because of the UML used to create diagrams, we maintain the compatibility with other unified modeling language based environments. Class and object diagrams are used in our case to describe the normal composition of the body environment and the elements involved in physiological processes. Machine stare diagram are used to decompose and represent complex pathologic events and to show the spatiality of processes. UML implementations allow us to aggregate blocks of structures for better interpretation.
Further development guidelines for this theme involve a wider area of phenomena represented in the visual paradigm as well as the development of tools than can work with existent data to output interactive diagrams.
Because the unrestricted natural medical language, there are many indeterminate or partially determined relations between elements that make the object of natural medical language.
References
1. James K.; James S. (1998). Mathematical Physilogy. Springer-Verlag, New-York.
2. Teodorescu E. (1968). Agresologie Chirurgicală. Editura Medicală, Bucureşti.
3. Diculescu I., D. Onicescu (1987). Histologie medical. Ed. Medicală Bucureşti.
(1) MEDICAL CYBERNETIC ELEMENTS IN COMPUTERIZED ASSISTED INTENSIVE THERAPY IN DOGS
(2) VISUAL PARADIGM OVER LOGICAL CIRCUITS IN VETERINARY MEDICINE
(3) OBSERVATIONS FOR OBTEINING THE ULTRAFINS SECTIONS ON THE LKB ULTROTOME
ISSN 1454-2382
Cumpănaşu F. ; V. Rus
Universitatea de Ştiinţe Agricole şi Medicină Veterinară
Facultatea de Medicină Veterinară
Cluj-Napoca
Observations for obteining the ultrafins sections on the LKB ultrotome
SUMMARY
During 11-03-2004/04.05.2004 in a stage of
professional training, I have been attending a course of electronic microscopy
at the Center Of Electronic Microscopy at Babes-Bolyai
University. I have effectively participated at the making of glass knives, at
the modeling of blocks for sectioning, at obtaining the ultra-fine sections
using LKB ultra-microtome and at contrasting the sections to examine at
transmission electronic microscope.
During this manual labors I have confronted
various technical problems, and I have solved these after many hours of
exercises and attentive observation. The solution may be: Diving of the
sections is remedying through a lowering water lever from the lake. The
appearance of the ununiform sections in thickness is
remedying trough the remodeling of the specimen closer the piece margins there
where the fixer and the resin actioned uniformly. The
obtaining of the sections with incomplete surface is prevented through modeling
of resin blocks with a day before the sectioning, so that the resin ends its
polymerization. The dispersion of the sections on the water surfaces is
remedying through degreasing of all tools.
Observations: The obtaining of the ultra-fine
sections at LKB ultra microtome is a delicate operation that needs a special
attention for each step of sectioning and a diferent
way of making for each specimen.
Observaţii privind obţinerea secţiunilor
ultrafine la microtomul LKB
REZUMAT
În perioada
11-03-2004/04.05.2004 în cadrul
unui program de pregătire
profesională am urmat un curs de tehnică electronomicropică în cadrul Centrului de Microscopie Electoronică al Universităţii Babeş-Bolyai.
Am participat efectiv la confecţionarea cuţitelor
de sticlă, fasonarea blocurilor în vederea
secţionării, la obţinerea
secţiunilor ultrafine.
În timpul acestor manopere m-am confruntat cu variate probleme tehnice, pentru care, după ore de exerciţii şi observaţie atentă am găsit soluţii de remediere: Alunecarea secţiunilor sub apă
se remediază prin coborârea nivelului apei din bacul de colectare. Apariţia secţiunilor neuniforme
ca grosime se remediază
prin remodelarea specimenului, mai aproape de periferia piesei. Obţinerea secţiunilor cu suprafaţă
incompletă se preîntâmpină
prin fasonarea blocurilor de răşină
cu o zi înainta secţionării pentru ca răşina să
îşi încheie polimerizarea. Dispersia secţiunilor pe
suprafaţa apei se remediază prin degresarea instrumentarului de laborator.
Concluzii: Obţinerea secţiunilor ultrafine la ultramicrotomul
LKB este o operaţiune delicată
care necesită acordare
unei atenţii deosebite fiecărei etape a secţionării şi acomodarea modului de lucru la cerinţele fiecărui preparat.
(1) MEDICAL CYBERNETIC ELEMENTS IN COMPUTERIZED ASSISTED INTENSIVE THERAPY IN DOGS
(2) VISUAL PARADIGM OVER LOGICAL CIRCUITS IN VETERINARY MEDICINE
(3) OBSERVATIONS FOR OBTEINING THE ULTRAFINS SECTIONS ON THE LKB ULTROTOME
ISSN 1454-2382
Cumpănaşu F. ; V. Rus
Universitatea de Ştiinţe Agricole şi Medicină Veterinară
Facultatea de Medicină Veterinară
Cluj-Napoca
Results of digitalized pricessing on electronmicroscopicaly images using the dedicated program
Image Pro Plus (ver4.5) and the graphic editor Adobe
Photoshop (ver7.0b)
SUMMARY
The image from the electron microscop
is rich in information for morphologists. For the others, the information conntent is often unaccesible.
Even interdisciplinary informational exchange need a complementary representation. Based
on aditional kit of information, achieved by the mean
of objectiv methodes, every
researcher can help for image interpretation, whatever his domain of activity
is. The results mediatization success is emphasize by
the simple nature of aditional information.
The results are obtained trough digital image analizing on Electron Microscopy Center of Babes-Bolyai
University: Trough 3D representation I estimate the local density of the Bowman membrane. Measuring the light
intensity I create the graphic profile of a section trough a collagen fiber.
Editing the color palette color table I obtain indexed color
image of a liphosom.
Using convolution filters I selectiv emphasize hepatocite components.
Observation: Digital image analysis is an impurtant step for research used for interdisciplinary
reports, for menteining and mediatization
of investigation results.
Rezultate ale prelucrării
digitalizate a imaginilor electronomicroscopice
cu ajutorul programului dedicat Image Pro Plus (ver4.5) şi
a editorului grafic Adobe
Photoshop (ver7.0b)
REZUMAT
Imaginea preluata le la microscopul electronic este bogataă în informaţie accesibilă morfologilor. Pentru toţi ceilalţi, informaţia conţinută este
adesea inaccesibila. Chiar schimbul interdisciplinar de informaţie
are nevoie de o completare a imaginii originale
electronomicroscopice. Ajutat
fiind de un set de informaţie adiţional, obţinut prin metode obiective, orice cercetator îşi poate aduce contribuţia la interpretarea imaginii electronomicroscopice în funcţie de priceperea sa dar indiferent
de domeniul de activitate. Succesul mediatizarii rezultatelor studiilor electronomicroscopiice este sensibil amplificat de natura simplificată a ifrormaţiei
adiţionale.
Rezultate obţinute prin analiza digitalizată
de imagini din arhiva Centrului de Microscopie Electronică al Universităţii
Babeş-Bolyai: Prin reprezentări tridimensionale
(shaded surface) am evaluat denditatea
locală a capsulei
Bowman. Măsurând intensitatea
luminoasă (pathline)
am determinat profilul grafic al unei secţiuni prin molecula de colagen. Editând tabela de culori (LUT) am obţinut reprezentări color ale aspectului
electronomicroscopic al liposomilor.
Folosind metode rgafice de filtrare (convolution
type) am evidenţiat structuri
morfologice ale hepatociteului.
Definind clase de obiecte
am separat şi grupat statistic ribozomi şi mitocondrii pe o secţiune prin hepatocit.
Observaţie: Analiza digitalizată a imaginilor reprezintă o etapă importantă a cercetării
utilă protocoalelor de comunicare, susţinere şi mediatizare a rezultatelor investigaţiilor
electronomicroscopice.
(1) MEDICAL CYBERNETIC ELEMENTS IN COMPUTERIZED ASSISTED INTENSIVE THERAPY IN DOGS
(2) VISUAL PARADIGM OVER LOGICAL CIRCUITS IN VETERINARY MEDICINE
(3) OBSERVATIONS FOR OBTEINING THE ULTRAFINS SECTIONS ON THE LKB ULTROTOME